Intrauterine programming of urinary calcium and magnesium excretion in children born to mothers with insulin dependent diabetes mellitus

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Intrauterine programming of urinary calcium and magnesium excretion in children born to mothers with insulin dependent diabetes mellitus.

BACKGROUND Offspring of diabetic rats have reduced urinary calcium and magnesium excretion compared with offspring of controls; these differences persist up to 16 weeks after birth, a time equivalent to young adulthood in humans. OBJECTIVES To test the hypothesis that urinary calcium and magnesium excretion would be lower in children born to mothers with insulin dependent diabetes mellitus (C...

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Insulin effect on Leptin Concentration in Children with New Onset Insulin Dependent Diabetes Mellitus

Objective: Serum Leptin concentration reflects the body fat mass. There is controversial reports about the insulin effect on serum Leptin concentration. We wanted to examine the effect of insulin therapy on serum Leptin in children with new onset type I diabetes. Materials and Methods: This was a Cross-Sectional study in Children's Medical Center on 34 children who had new onset type I diabe...

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Urinary excretion of calcium and magnesium in children.

Ghazali, S., and Barratt, T. M. (1974). Archives of Disease in Childhood, 49,97. Urinary excretion of calcium and magnesium in children. Urine calcium excretion in healthy children was 2 38±0 66 (SD; no. 52) mg/kg per 24 hr and urinary magnesium excretion was 2 82±0 79 (SD; no. 23). The 24-hour urine calcium excretion could be predicted with reasonable confidence from the calcium/ creatinine co...

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Urinary biotinidase and alanine excretion in patients with insulin-dependent diabetes mellitus.

Twenty-four-hour urine specimens from 21 juvenile insulin-dependent diabetics and 10 healthy controls were compared with respect to biotinidase activity and alanine content. Urinary biotinidase activity was analysed by a newly developed high-performance liquid chromatography (HPLC) method. It was found that the excretion of biotinidase in urine was elevated in diabetics (7.02 mU/d; p < 0.005) a...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition

سال: 2005

ISSN: 1359-2998,1468-2052

DOI: 10.1136/adc.2004.052795